ythdf2 yth domain family 2 Search Results


gene exp ythdf2 mm00661925 m1  (Thermo Fisher)
94
Thermo Fisher gene exp ythdf2 mm00661925 m1
Gene Exp Ythdf2 Mm00661925 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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yth domain family 2  (Proteintech)
96
Proteintech yth domain family 2
Yth Domain Family 2, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ythdf2+yth+domain+family+2/YTHDF2+Antibody/pmc07845411-98-15-21
Average 96 stars, based on 1 article reviews
yth domain family 2 - by Bioz Stars, 2026-08
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ythdf2 yth domain family 2  (Novus Biologicals)
92
Novus Biologicals ythdf2 yth domain family 2
Fig. 3 MLL1 promotes RBM15 expression by increasing H3K4me3 modification; RBM15 enhances m6A modification to promote <t>YTHDF2</t> binding to TRIM72 mRNA and degrade TRIM72, thereby inhibiting TRIM72 expression. A: Analysis of the enrichment of MLL1 and H3K4me3 on RBM15 promoter in tissues (n = 6) and cells (n = 3) by ChIP. B-C: Detection of RBM15 and TRIM72 expressions in tissues (n = 6) and cells (n = 3) by qRT-PCR and Western blot. D: Quantitative analysis of m6A modification in tissues (n = 6) and cells (n = 3). E: Analysis of the m6A modification on TRIM72 mRNA and the enrichment of YTHDF2 in tissues (n = 6) and cells (n = 3) by RIP. F: Detection of TRIM72 mRNA stability in cells (n = 3) by actinomycin D; HTR-8/SVneo cells were transfected with sh-YTHDF2, with sh-NC as the control. G-H: Detection of YTHDF2 expression in cells (n = 3) by qRT-PCR and Western blot. Data in panels AEF were analyzed by two-way ANOVA, and data in panels BCD were analyzed by one-way ANOVA, followed by Tukey’s multiple comparisons test. Data in panels GH were analyzed by t test. **P < 0.01
Ythdf2 Yth Domain Family 2, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ythdf2+yth+domain+family+2/YTHDF2+Recombinant+Protein+Antigen/pm39709463-103-34-53
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ythdf2 yth domain family 2 - by Bioz Stars, 2026-08
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anti yth domain family 2  (Cell Signaling Technology Inc)
95
Cell Signaling Technology Inc anti yth domain family 2
Fig. 3 MLL1 promotes RBM15 expression by increasing H3K4me3 modification; RBM15 enhances m6A modification to promote <t>YTHDF2</t> binding to TRIM72 mRNA and degrade TRIM72, thereby inhibiting TRIM72 expression. A: Analysis of the enrichment of MLL1 and H3K4me3 on RBM15 promoter in tissues (n = 6) and cells (n = 3) by ChIP. B-C: Detection of RBM15 and TRIM72 expressions in tissues (n = 6) and cells (n = 3) by qRT-PCR and Western blot. D: Quantitative analysis of m6A modification in tissues (n = 6) and cells (n = 3). E: Analysis of the m6A modification on TRIM72 mRNA and the enrichment of YTHDF2 in tissues (n = 6) and cells (n = 3) by RIP. F: Detection of TRIM72 mRNA stability in cells (n = 3) by actinomycin D; HTR-8/SVneo cells were transfected with sh-YTHDF2, with sh-NC as the control. G-H: Detection of YTHDF2 expression in cells (n = 3) by qRT-PCR and Western blot. Data in panels AEF were analyzed by two-way ANOVA, and data in panels BCD were analyzed by one-way ANOVA, followed by Tukey’s multiple comparisons test. Data in panels GH were analyzed by t test. **P < 0.01
Anti Yth Domain Family 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ythdf2+yth+domain+family+2/YTHDF2+Antibody/10__1096_slash_fj__202400664r-93-67-74
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anti yth domain family 2 - by Bioz Stars, 2026-08
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Image Search Results


Fig. 3 MLL1 promotes RBM15 expression by increasing H3K4me3 modification; RBM15 enhances m6A modification to promote YTHDF2 binding to TRIM72 mRNA and degrade TRIM72, thereby inhibiting TRIM72 expression. A: Analysis of the enrichment of MLL1 and H3K4me3 on RBM15 promoter in tissues (n = 6) and cells (n = 3) by ChIP. B-C: Detection of RBM15 and TRIM72 expressions in tissues (n = 6) and cells (n = 3) by qRT-PCR and Western blot. D: Quantitative analysis of m6A modification in tissues (n = 6) and cells (n = 3). E: Analysis of the m6A modification on TRIM72 mRNA and the enrichment of YTHDF2 in tissues (n = 6) and cells (n = 3) by RIP. F: Detection of TRIM72 mRNA stability in cells (n = 3) by actinomycin D; HTR-8/SVneo cells were transfected with sh-YTHDF2, with sh-NC as the control. G-H: Detection of YTHDF2 expression in cells (n = 3) by qRT-PCR and Western blot. Data in panels AEF were analyzed by two-way ANOVA, and data in panels BCD were analyzed by one-way ANOVA, followed by Tukey’s multiple comparisons test. Data in panels GH were analyzed by t test. **P < 0.01

Journal: Biology direct

Article Title: MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis.

doi: 10.1186/s13062-024-00572-0

Figure Lengend Snippet: Fig. 3 MLL1 promotes RBM15 expression by increasing H3K4me3 modification; RBM15 enhances m6A modification to promote YTHDF2 binding to TRIM72 mRNA and degrade TRIM72, thereby inhibiting TRIM72 expression. A: Analysis of the enrichment of MLL1 and H3K4me3 on RBM15 promoter in tissues (n = 6) and cells (n = 3) by ChIP. B-C: Detection of RBM15 and TRIM72 expressions in tissues (n = 6) and cells (n = 3) by qRT-PCR and Western blot. D: Quantitative analysis of m6A modification in tissues (n = 6) and cells (n = 3). E: Analysis of the m6A modification on TRIM72 mRNA and the enrichment of YTHDF2 in tissues (n = 6) and cells (n = 3) by RIP. F: Detection of TRIM72 mRNA stability in cells (n = 3) by actinomycin D; HTR-8/SVneo cells were transfected with sh-YTHDF2, with sh-NC as the control. G-H: Detection of YTHDF2 expression in cells (n = 3) by qRT-PCR and Western blot. Data in panels AEF were analyzed by two-way ANOVA, and data in panels BCD were analyzed by one-way ANOVA, followed by Tukey’s multiple comparisons test. Data in panels GH were analyzed by t test. **P < 0.01

Article Snippet: R: T G A T A A A A G C C C A G C C C A G T A C Note: MLL1: mixed-lineage leukemia 1; RBM15: RNA binding motif protein 15; YTHDF2: YTH domain family 2; TRIM72: tripartite motif containing 72; ADAM9: ADAM metallopeptidase domain 9; GAPDH: glyceraldehyde-3-phosphate dehydrogenase nb600-256, NOVUS) and H3K4me3 (1:1000, ab213224, Abcam) at 4 °C overnight.

Techniques: Expressing, Modification, Binding Assay, Quantitative RT-PCR, Western Blot, Transfection, Control

Fig. 9 MLL1 promotes RBM15 expression by increasing H3K4me3 on the RBM15 promoter; RBM15 upregulates TRIM72 mRNA m6A modification, pro motes the binding between YTHDF2 and TRIM72, and then degrades TRIM72 mRNA and inhibits TRIM72 expression, thereby reducing the ubiquitination degradation of ADAM9, stabilizing the expression of ADAM9, and eventually promoting ferroptosis of trophoblasts and aggravating PE

Journal: Biology direct

Article Title: MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis.

doi: 10.1186/s13062-024-00572-0

Figure Lengend Snippet: Fig. 9 MLL1 promotes RBM15 expression by increasing H3K4me3 on the RBM15 promoter; RBM15 upregulates TRIM72 mRNA m6A modification, pro motes the binding between YTHDF2 and TRIM72, and then degrades TRIM72 mRNA and inhibits TRIM72 expression, thereby reducing the ubiquitination degradation of ADAM9, stabilizing the expression of ADAM9, and eventually promoting ferroptosis of trophoblasts and aggravating PE

Article Snippet: R: T G A T A A A A G C C C A G C C C A G T A C Note: MLL1: mixed-lineage leukemia 1; RBM15: RNA binding motif protein 15; YTHDF2: YTH domain family 2; TRIM72: tripartite motif containing 72; ADAM9: ADAM metallopeptidase domain 9; GAPDH: glyceraldehyde-3-phosphate dehydrogenase nb600-256, NOVUS) and H3K4me3 (1:1000, ab213224, Abcam) at 4 °C overnight.

Techniques: Expressing, Modification, Binding Assay, Ubiquitin Proteomics